Detox and binders
Does penicillamine lower blood lead?
In a retrospective cohort, children treated with D-penicillamine had a 33 percent fall in blood lead over a mean of 76 days, and untreated children did not. Adverse reactions occurred in 33 percent, including leukopenia, rash, and platelet depression, and 10 percent stopped because of a reaction. This is not a randomized trial.
Study
Shannon and colleagues (1988) compared 84 treated children with 37 untreated children. Blood lead was 25 to 40 µg/dL. Seventy-six percent of treated children reached 25 µg/dL or below. Ten percent were treatment failures. PMID 3361395, doi:10.1016/s0022-3476(88)83212-8.
Sources
Heavy Metal Index
Heavy Metal Index: Lead. This Heavy Metal Index URL returned HTTP 200 on 15 October 2026. Figures on this page are not copied from that index. They come from the sources named above.
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This page summarizes cited documents. It does not diagnose or prescribe. Reviewed 15 October 2026.