METALLOPATHY Evidence on heavy metals in people

Static evidence pages. Grades A to F. Sources named.

Browse pages

Detox and binders

Does N-acetylcysteine lower blood lead in exposed workers?

In 171 men with ongoing occupational lead exposure, blood lead fell from baseline in groups assigned to N-acetylcysteine for 12 weeks. Erythrocyte glutathione rose 5 percent and 6 percent at 400 and 800 mg/day. There was no placebo, blinding was not stated, and exposure continued. No glutathione trial with a metal outcome was located. Glutathione is graded on its own page.

Study

Kasperczyk and colleagues (2013) randomized 171 workers, 49 of them controls, to no treatment or one of three doses. doi:10.3109/15563650.2013.802797. PMID 23731375. Later papers from the same group were not counted as independent trials.

Related pages

Sources

  1. Kasperczyk et al. 2013, doi:10.3109/15563650.2013.802797, PMID 23731375

Heavy Metal Index

Heavy Metal Index: Lead. This Heavy Metal Index URL returned HTTP 200 on 15 October 2026. Figures on this page are not copied from that index. They come from the sources named above.

What's safe to buy

The Heavy Metal Tested and Certified public register listed no licensees on 15 October 2026. That page reported 0 certified brands and 0 certified products, and it stated that no brand has completed the three-lot baseline. A specimen layout on the register is an illustration, not a licensee. This page does not name or rank any brand.

The program states that certification is a measurement of a product against a published limit, not a statement that the product is safe. If a licensee is later listed for this category, it will be on the register.

This page summarizes cited documents. It does not diagnose or prescribe. Reviewed 15 October 2026.